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Science (from the Latin word scientia, meaning "knowledge") is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe.

The earliest roots of science can be traced to Ancient Egypt and Mesopotamia in around 3500 to 3000 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to explain events of the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages but was preserved in the Muslim world during the Islamic Golden Age. The recovery and assimilation of Greek works and Islamic inquiries into Western Europe from the 10th to 13th century revived natural philosophy, which was later transformed by the Scientific Revolution that began in the 16th century as new ideas and discoveries departed from previous Greek conceptions and traditions. The scientific method soon played a greater role in knowledge creation and it was not until the 19th century that many of the institutional and professional features of science began to take shape.

Modern science is typically divided into three major branches that consist of the natural sciences (e.g., biology, chemistry, and physics), which study nature in the broadest sense; the social sciences (e.g., economics, psychology, and sociology), which study individuals and societies; and the formal sciences (e.g., logic, mathematics, and theoretical computer science), which study abstract concepts. There is disagreement, however, on whether the formal sciences actually constitute a science as they do not rely on empirical evidence. Disciplines that use existing scientific knowledge for practical purposes, such as engineering and medicine, are described as applied sciences.

Science is based on research, which is commonly conducted in academic and research institutions as well as in government agencies and companies. The practical impact of scientific research has led to the emergence of science policies that seek to influence the scientific enterprise by prioritizing the development of commercial products, armaments, health care, and environmental protection.

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The tectonic plates of the world were mapped in the second half of the 20th century.
Plate tectonics (from Greek τέκτων, tektōn "builder" or "mason") is a theory of geology which was developed to explain the observed evidence for large scale motions within the Earth's crust. The theory encompassed and superseded the older theory of continental drift from the first half of the 20th century and the concept of sea floor spreading developed during the 1960s.

The outermost part of the Earth's interior is made up of two layers: above is the lithosphere, comprising the crust and the rigid uppermost part of the mantle. Below the lithosphere lies the asthenosphere, which is a more viscous zone of the mantle. Although solid, the asthenosphere has very low shear strength and can flow like a liquid on geological time scales. The deeper mantle below the asthenosphere is more rigid again.

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A Persian astrolabe, used for determining the time at both day and night.
Credit: Andrew Dunn

An 18th Century Persian astrolabe used for determining the time at both day and night. The points of the curved spikes on the front rete plate mark the positions of the brightest stars, the name of each star being labeled at the base of each spike. The back plate, or mater, is engraved with projected coordinate lines. From the Whipple Museum of the History of Science collection.

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Newton at age 46 in Godfrey Kneller's 1689 portrait.
Isaac Newton, English physicist, mathematician, astronomer, inventor, philosopher and alchemist. A man of profound genius, he is widely regarded as the most influential scientist in history. He is associated with the scientific revolution and the advancement of heliocentrism. Among his scientific accomplishments, Newton wrote the Philosophiae Naturalis Principia Mathematica, wherein he described universal gravitation and, via his laws of motion, laid the groundwork for classical mechanics. With Gottfried Wilhelm Leibniz he is credited for the development of differential calculus. Newton was the first to promulgate a set of natural laws that could govern both terrestrial motion and celestial motion, and is credited with providing mathematical substantiation for Kepler's laws of planetary motion, which he expanded by arguing that orbits (such as those of comets) could include all conic sections (such as the ellipse, hyperbola, and parabola).

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